Table 8.

Examples of alignment between learning goals, practice (clicker, homework) questions, and exam questions

ExampleLearning GoalPractice (Clicker, Homework) QuestionExam Question
1Given a change in a parameter that influences net driving force, equilibrium potential, or resting membrane potential, predict how this influences net driving force, equilibrium potential, resting membrane potential, or current across the membrane.
  • If the external concentration of sodium is doubled, will the resting membrane potential change?

  • If the sodium permeability is transiently doubled, will the resting membrane potential change?

A drug is applied to a neuron that temporarily blocks a substantial portion (~65%) of the resting K+ ion channels in the neuron's membrane preventing any ions from moving through these channels. 
  • What effect, if any would this drug have on the equilibrium potential of K+ in this neuron?

  • What effect, if any, would this drug have on the resting membrane potential of the neuron?

2Predict the type of ion channel in a given functional region of a neuron for a novel scenario.What type of gated ion channel would you most likely expect to find at the input region of the motor neuron (arrow) in the figure above?Considering the 4 types of gating stimuli, which type of gated ion channel would you expect to be characteristic of the input region of this sensory afferent?
3Calculate time and length constants, input resistance and input capacitance from graphical data (for ex., I–V data) or numerical valuesCalculate the input resistance for this neuron, based on these I–V data.
Calculate the conductance(s) for this ion channel (based on the I–V data shown).
Calculate the conductance(s) for this ion channel (based on the I–V data shown).
4Differentiate between electrical, chemical, and net driving forces, and, given a set of data, predict the direction or relative magnitude of the current flow (net or ionic) due to these forces and its effect on the membrane potential.If the membrane potential is −60 mV and the equilibrium potential for chloride is −80 mV in a typical cell, what are the directions of the electrical, chemical, and net driving forces acting on chloride?What are the directions of the chemical, electrical, and net driving forces acting on K+ in a typical neuron when the membrane potential is 55 mV?